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Description
Current status and applications of genome-scale metabolic models

Interestingly, global IGF-I KO, Cart IGF-IR / , and TamCar IGF-IR / mice all show increased expression of PTHrP protein and RNA, but decreased Ihh expression in their growth plates, indicating a disrupted PTHrP/Ihh feedback loop (26,32)

T.SingerW

Authors contributions FB mined and analyzed the data, participated in the design of the review, and drafted the manuscript

[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Baker R.D
