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doi: 10.1089/zeb.2015.1215, PMID: [DOI] [PubMed] [Google Scholar] 59.Kumar A, Kalonia H

Thats not just defense, its reversal
This mechanism effectively functions as an in situ vaccine, transforming the tumor microenvironment from cold to hot by promoting dendritic cell activation and T-cell infiltration

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If the most popular version of the .NET Framework didnt support .NET Standard 2.0, no one would write .NET Standard 2.0 libraries, which would hamstring .NET Core 2.0 as well