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The genes encoding PFK-L (PFKL) and PFK-M (PFKM) are located on chromosomes 21q22.3 and 12q13.3, respectively

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mansoni juvenile worms, the LD 50 of PZQ (413 M) is inferior to that of inhibitors 1 - 5 (7.2 60% reduction in worm burden, a significantly higher efficacy than observed for treatment with PZQ in previous studies 13 , which had 0% reduction at 21 and 28 d.p.i