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Description
Methylseleninic acid synergizes with tamoxifen to induce caspase-mediated apoptosis in breast cancer cells

PD-associated mutations (e.g., acid -glucocerebrosidase (GBA1)) cause lysosomal storage disorders, reducing degradation capacity

PMC 2821669

The result is oxidative stress (OS) which is linked to numerous disease processes including cognitive decline (Alzheimers disease) and other age-related conditions like cancer, cardiovascular disease, and diabetes

MOTS-c has no relationship to this axis at all
