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Abstract The pharmacological effects of intraperitoneal (i.p.) and intranasal (i.n.) administration of the peptides selank (300 g/kg/day), noopept (1 mg/kg/day), and semax (0.6 mg/kg/day), which are known to possess anxiolytic and nootropic properties, were compared by studying the elevated-plus-maze (EPM) behavior of inbred BALB/c and C57BL/6 mice, and studying their effects on NMDA- and mGluII- receptors in the brain
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found that ACSL4 gene knockout could attenuate ischemic brain injury while over-expression aggravated IS (Doll and Conrad, 2017

ECSOD, Extracellular superoxide dismutase
In addition to this, astrocytic ApoE-HDL particles contain a diverse range of neuronal regulatory miRNAs that ultimately promote neuronal functioning (Li et al., 2021)
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