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Therefore, similar to the transport of GAA from the kidneys to the liver for creatine synthesis, the GAA produced in certain neural cells must be transported into GAMT expressing cells in order for brain creatine synthesis

The dermis (the thick middle layer of skin) is composed of a complex network called the extracellular matrix, or ECM

Pelletier, J., Thomas, G

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Patients who have a deteriorating response to L-dopa, experience fluctuations in response to L-dopa, or have a limited clinical response to L-dopa secondary to an inability to tolerate higher doses are appropriate candidates