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Description
HOPE revealed more flexibility in the native GSR structure than in the mutant structure
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B.ShenhavR.Matcovitch-NatanO.TothB.LemzeD.GolanM.et al (2017)

Early diagnosis through genetic testing and metabolic screening is crucial, as prompt treatment with parenteral hydroxocobalamin, often combined with other adjunct therapies, can mitigate disease progression and improve outcomes

Apart from one patient, all were identified by whole-exome sequencing or through candidate gene panels [3]

It is important to note that these dosage suggestions are not based on scientifically validated evidence and should be considered speculative
