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With a deeper understanding of ferroptosis during the occurrence and progression of cerebral I/R injury, new therapies to treat ischemic nerve damage by interfering with the molecular mechanism of ferroptosis are expected to be realized to some extent

Focus of Cellular Alteration Introduction Foci of cellular alteration are common in rodent studies greater than duration of twelve months and may be seen in short duration toxicity studies following exposure to certain xenobiotics

TNF: tumor necrosis factor

Elife 12 , e84391 (2023)

Enzyme histochemistry has shown that GDH is present in rat hippocampal dendritic layers and that GDH activity increases in tandem with the postnatal maturation of synaptic structures (Schnzel and Wolf, 1982)