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To assess the role of 3-AR in mediating these effects, researchers examined AOD9604 and hGH treatment in 3-KO mice

In mouse models of highfat dietinduced obesity, it treatment significantly reduced mRNA and protein expression of TNF, IL6, and other inflammatory factors in adipose tissue and decreased macrophage infiltration - a hallmark of adipose inflammation

Thymosin beta-4 has human clinical data, but TB-500 itself does not have completed human musculoskeletal trials
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