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Moreover, Study conducted on mouse model reported that LPS can downregulate occluding (a protein in tight junction) in the intestinal epithelial cells and upregulate TNF-, which promotes the expression of -synuclein (32, 33)

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Consuming large amounts quickly, such as in binge or high-intensity drinking episodes, results in rapid BAC increases
10 VGLUT1 and VGLUT2 are widely coexpressed in multiple regions of the CNS, playing predominant roles in central neural circuits
