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After CBD treatment, in human leukemia, in thymocytes and EL-4 thymoma cells, apoptosis was accompanied by an increased production of ROS and activation of NAD(P)H oxidases NOX4 and p22phox, further supporting the role of ROS in CBD-induced apoptosis [150,151]

Frontiera MS, Stabler SP, Kolhouse JF, and Allen RH (1994)

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