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Sustained ER stress contributes to oxidative lipid damage and facilitates ferroptotic signaling (169)

The integration of AI and automated systems is expected to replace labor-intensive manual scoring, enhancing reproducibility, speed, and potentially improving cost-effectiveness.4, 5 Different strategies are also being explored to reduce the CT-related radiation risk, especially in younger populations undergoing repeated imaging, such as patients with cystic fibrosis (CF) or primary ciliary dyskinesia (PCD)

Results Absence of promoter proximal NRF2 at NRF2 signature genes To identify critical pathways downstream of NRF2 activation in cancer, we sought to define a core set of genes and other features associated with NRF2-dependent growth across an expansive panel of cancer cell lines

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Broad RTK-targeted therapy overcomes molecular heterogeneity-driven resistance to cetuximab via vectored immunoprophylaxis in colorectal cancer
