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doi: 10.1016/j.neurobiolaging.2007.07.005
Some of these drugs have been confirmed their effectiveness and safe tolerance
Factors contributing to the suboptimal performance of drugs include the selection of drug targets, the use of biomarkers and animal models in experimental designs, and other issues such as late treatment initiation, dose-dependent side effects, challenges in BBB permeability, and the heterogeneous presentation of patients
or the decision to submit the paper for publication
