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This hypothesis was tested using iron chelators and iron supplements during erastin-mediated ferroptosis [17]

Sacpic staining results also showed that the proportion of primary active hair follicles has no significant change, while the proportion of secondary active hair follicles in the KO group was significantly higher than that in the control group

This macrophage reprogramming is associated with SFN-mediated inhibition of the transcription factor c-Myc, which normally drives M2 polarization, and concurrent activation of the Nrf2 pathway that favors M1-associated gene expression profiles (78)

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