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Cell, 7 (11): 18051813

doi: 57

Michelen M, Manoharan L, Elkheir N, Cheng V, Dagens A, Hastie C, et al

Methotrexate (MTX) is an antimetabolite that reversibly binds dihydrofolate reductase, inhibiting the conversion of dihydrofolate to tetrahydrofolate and thus disrupting DNA synthesis, repair, and cellular replication

He started working on mycobacteria as a postdoctoral fellow at the University of Melbourne in Australia in the lab of Malcolm McConville
