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Once at the tissue level, E2 exerts its actions through estrogen receptors and (ER and ER), as well as membrane-associated receptors mediating rapid non-genomic signaling [30,31]

doi: 10.1016/j.brainresbull.2008.12.001 Summary Keywords bilirubin, dopaminergic neurons, inflammation, neurodevelopment, oxidative stress, Parkinson's disease Citation Zhang Y, Liu H, Cao H, Deng M, Han Z, Wu X, Wan Q, Wang R, Xu Y, Lai J, Jiang Y, Gong L, Liu Z, Lai K and Shi H (2026) Neuroprotective role of bilirubin in Parkinson's disease

The most important are the 78 kDa glucose regulatory protein (GRP78) and protein disulfide isomerase (PDI)