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The fumarate accumulation, which occurs as a consequence of FH mutations, results in the formation of hereditary papillary renal carcinomas, whereas the succinate accumulation, that occurs as a consequence of SDH mutations, results in the formation of hereditary paragangliomas (PGLs)

Vitamin B12 Supports DNA replication and hemoglobin production, increasing oxygen delivery to skin cells and combating the dull, fatigued appearance of anemia

In order to remove this excess fat, some people may go to drastic actions, such as extreme diets or surgical procedures