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Production of a novel superoxide dismutase by Escherichia coli and Pichia pastoris and analysis of the thermal stability of the enzyme

The objective of the current study was to demonstrate the therapeutic potential of oral administration of glutathione in an open-label, single-arm, multicenter, pilot study prior to subsequent large-scale clinical trials

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however, it did not alter circulating glucocorticoid amount in rats treated with NAC, showing that antioxidants abolish the ability of glucocorticoids to perform negative feedback of the HPA axis