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Overall, the limited impact of NAC on mutational profiles suggests that chemotherapy exerts only modest selective pressure on tumor genomic architecture, and that genetic mutation dynamics alone are unlikely to be the primary drivers of recurrence in EC

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For example, in the naming of the principal enzyme involved in the oxidation of ethanol to acetaldehyde, CYP2E1, the CYP denotes the cytochrome P450 family, the 2 denotes the subfamily, the E denotes ethanol, and the 1 denotes the specific isozyme

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