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Nutrition 11:117120 Shen T, Zhao Q, Luo Y, Wang T (2022) Investigating the role of zinc in atherosclerosis: a review

Preclinical studies have shown that curcumin enhances the cleavage of caspase-8 and caspase-3, suggesting a dual mechanism promoting apoptosis

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One theory is that due to the association between increased abundance of hybrid Insulin/IGF-1 receptors on target human tissues and elevated plasma insulin observed in patients with hyperinsulinemia, that these hybrid IR receptors may cause insulin resistance in certain human tissues