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PMCID: PMC3056539
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Because S(+)KET has higher affinity for NMDA receptors than R()KET, S(+)KET has been developed and later approved by the Food and Drug Administration as a clinical antidepressant (Hashimoto, 2019)
The group came to a consensus based on their clinical impression and supported by a review of the most recent randomized controlled trial, which was selected on the basis of a joint assessment of validity for clinical purposes
claimed that metabolic biomarkers, including methylation-redox, have 97% precision (sensitivity 72% and specificity 63%)
