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However, it contains a cyanide molecule that the body must remove during metabolism

PARP inhibitors (olaparib, niraparib, rucaparib) have revolutionised maintenance therapy for BRCA-mutated ovarian cancer while exhibiting minimal off-target toxicity toward dormant follicles [135,136,137,138], whose low replicative rate renders them less dependent on poly-ADP-ribose-polymerase activity [139]

The cysteine oxidation code sections) and enabling pathway-level analysis across protein networks and sulfenic acid capture with dimedone/DAz-2type chemistries traps Cys-SOH in situ, but calls should be corroborated with orthogonal cysteine-state profiling (e.g., differential alkylation or redox-switch back-ups) to prevent over-interpretation (Anjo et al

Homogeneity of variance was checked using Levenes test