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In general, it should be noted that microRNAs mediate impaired neurogenesis, lipid metabolism, amyloid and tau protein, angiogenesis, development of neuroinflammation, and oxidative stress, which is accompanied by loss of synaptic contacts, impaired neuroplasticity and cognitive functions (Figure 8)

Allen JD, Brinkhuis RF, van Deemter L, Wijnholds J, Schinkel AH (2000) Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance

NAC works by refilling intracellular glutathione levels, which is an important antioxidant that decreases oxidative stress and cellular damage

Semi-quantitative comparison of MALDI-FTICR MSI and LC-MS/MS datasets 0.8 mm 2 regions of healthy and tumor regions were isolated from three consecutive tissue sections for localized protein identification and relative quantitation

Abbreviations AA: Ascorbic acid ABA: Abscisic acid APX: Ascorbate peroxidase CAT: Catalase DEP: Differentially expressed proteins EBR: 24-Epibrassinolide GA: Gibberellic acid GB: Glycine betaine GPX: Guaiacol peroxidase GR: Glutathione reductase GSH: Glutathione IAA: Indole-3-acetic acid LOX: Lipoxygenase MDA: Malondialdehyde MDHAR: Monodehydroascorbate reductase NAA: -Naphthalene acetic acid POD: Peroxidases ROS: Reactive oxygen species SA: Salicylic acid SNP: Sodium nitroprusside SOD: Superoxide dismutase References Abdel Latef AAH, Akter A, Tahjib-Ul-Arif M