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In genetically confirmed NSD2 cases, respiratory infections and immunodeficiency, including IgA and IgG3 hypogammaglobulinemia, were observed, but immunoglobulin data were limited (4 patients per subtype) (92, 9799)

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Periodontal disease affects nearly half of adults over 30 in the United States, and the research is consistent that most of that damage accumulates gradually, in the interdental spaces and along the gumline that manual and standard electric brushes chronically under-clean

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