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Your body can develop tolerance, so protocols typically run 8-12 weeks followed by a break

[DOI] [PubMed] [Google Scholar] 56.Vargas F., Rodrguez-Gmez I., Prez-Abud R., Vargas Tendero P., Baca Y., Wangensteen R

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This theory is that free radicals, as by-products of mitochondrial oxidative metabolism, cause cumulative cellular damage that results in overall loss of organismal fitness over time

In this study, the selected factors were pressure (80, 140, and 200 bar) and temperature (40, 50, and 60 C), while the response variable was oil yield (%) (Supplementary Table S1)