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A compelling amount of research demonstrates that most people with Parkinsons symptoms have a serious deficiency of B vitamins, especially vitamin B12 and that the levels are lower in patients with Parkinsons compared with people without the condition

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The qPCR experimental results indicated that knocking down JAB1 or CUL4B led to a decrease in the mRNA expression levels of downstream metabolic genes involved in fatty acid oxidation (Supplementary Fig