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The authors reported improved Morris water maze performance (reduced escape latency over the training days), increased synaptophysin (a synaptic-density marker), and lower IL-1 and TNF-, with effects attributed to PI3K/AKT signaling
Thats because the FDA has now VERY NARROWLY defined what homologous use is for these products

Topical serums produce localized surface-level effects in the skin layers they penetrate, which is limited by the skin barrier
NPro was suggested to represent an NA negative control, due to its negative charge at neutral pH, thus preventing its diffusion into cells and subsequent metabolic activation into DNA-reactive metabolites (Chu and Magee 1981

Gastric acid has a pH of 1 to 2, a force that would dissolve most tissues in the body
