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Pisano et al

Safety and efficacy of vitamin B in cancer treatments: a systematic review

Nephron 92, 743745

282 Alternatively, intravenous injection of human umbilical cord blood mesenchymal stem cell-derived exosomes into the portal vein of hepatic I/R mice upregulated the expression of miR-1246 and activate the Wnt/-catenin pathway by targeting and negatively regulating GSK-3

In contrast to the IVW approach which sets the intercept term to zero, the introduction of the aforementioned parameter in the MR-Egger framework enables assessment of pleiotropic effects that may be distributed independently from those of instrumental variables (IVs) on outcomes through exposures
