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It is proposed that H5 serves as a critical hinge-like domain that facilitates domain swapping events (Figure 3a) [26], where the remainder of the truncated C-terminal domain (H6-H7) from one APOA1 molecule extends across and interacts with the neighboring APOA1 molecule, stabilizing the dimeric configuration

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123 TRIM46-induced ferroptosis in human retinal capillary endothelial cells involves glutathione peroxidase 4 (GPX4) ubiquitination and degradation, which are related to iron metabolism and DR pathology

Molecular mechanisms of KDM5A in cellular functions: facets during development and disease