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Because antioxidants provide natural stress resistance and pathogen defense, there is interest in harnessing antioxidant systems to increase crop yield and resilience (Arnao and Hernandez-Ruiz 2015

In cancer research, IGF1 LR3 serves as a tool for studying the role of IGF-1 signaling in tumor growth and progression

Therefore, further research confirmed that CHE is a functional inhibitor of Bcl-xL, bound at the BH region of Bcl-xL (Zhang et al., 2006), and was reported to interfere specifically with the interaction between Bcl-xL and Bax, which act directly on the mitochondria from tumor cells and lead to the release of Cyt-c

Although the reaction of PhSeBr and 1a generating the SeN intermediate INT1-Se is endothermic by 12.6 kcal mol 1 , INT1-Se may readily undergo a Se-centred [2,3]-sigmatropic rearrangement to generate an ortho -Se = N substituted dearomatized species ( INT2-Se ) via TS1-Se , with a barrier of 12.7 kcal mol 1