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Clinical trials tested doses ranging from 250mcg to 1mg daily, with most protocols settling around 300-500mcg for optimal fat metabolism support

compared a number of outcomes in a patient cohort of individuals with alcoholic polyneuropathy of a duration of less than two years who were treated with one of three formulations administered orally three times daily for 12 weeks: (A) B1 250 mg, B2 10 mg, B6 250 mg, B12 20 g

According to NICE Clinical Knowledge Summary guidance, patients with neurological involvement should receive more intensive initial treatment to optimise recovery potential

TL;DR Vitamin B12 is crucial for DNA production, cell replication (especially in the gut), brain function, and red blood cell formation, but gluten sensitivity can impair its absorption in the stomach and small intestine

So this audit achieved its goal, life saving B12 injections were cut, at this point, from monthly to one injection every two months