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The 12mg dose from Phase 2 trials represents the high end
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For the 2 AR, ubiquitination on lysines in both the carboxyl tail and the third intracellular loop is critical for lysosomal targeting [79]
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Mov Disord off J Mov Disord Soc 32:16311636 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhang S et al (2015) Plasma homocysteine, vitamin B12 and folate levels in multiple system atrophy: a case-control study
