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Yagoda N, Von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, et al

The tumor burden was monitored by following the volume of the tumor

[PubMed: 1290954] 316

It has been shown that hypoxia decreases insulin sensitivity in mice and might ultimately increase expression of the lipogenic genes sterol-regulatory-element-binding protein-1c (SREBP-1c), peroxisome-proliferator-activated receptor- (PPAR-), acetyl-CoA carboxylase 1 (ACC1) and acetyl-CoA carboxylase 2 (ACC2)

The rigor of experimental design, the complex interactions of immune responses, off-target effects of reagents and genetic interventions on inflammation, as well as the role of inflammatory mediators in AILI should be considered