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The first symptom is pain or discomfort, which can be mild or intense

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According to a systematic review and meta-analysis based on the benefits of conservative treatment and minimal risks associated with the therapy, it should be the front line of treatment (2)

116 As previously noted, in a randomized controlled trial in 468 men with infertility and sperm abnormalities, 600 mg NAC in combination with 200 mcg selenium daily improved semen quality, increased testosterone, LH, and inhibin B levels, and decreased FSH levels after 30 weeks