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On the other hand, the vicious course induced by high intra-abdominal pressure can be simultaneously initiated and perpetuated from different sites (it should be noted that intracranial hypertension may essentially cause pulmonary edema and impair pulmonary circulation (Chen, 2009))

In general, the more conversion steps required, the less potent and less irritating they are

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doi: 10.1093/qjmed/hcz046

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