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Although IL-10 is important to downregulate an exacerbated immune response, the presence of IL-10 in concomitance with pro-inflammatory cytokines leads to a non-specific and non-resolutive immune response and has been associated to worse clinical evolution ( Unfortunately, the use of NAC as treatment adjuvant does not change clinical evolution and laboratorial parameter when compared to standard protocol

Bibcode:2004BiEss..26..778A

[DOI] [PMC free article] [PubMed] [Google Scholar] [207].Imber M, Loi VV, Reznikov S, Fritsch VN, Pietrzyk-Brzezinska AJ, Prehn J, Hamilton C, Wahl MC, Bronowska AK, Antelmann H, The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus, Redox Biol

Some patients start with a single session, while others benefit from a planned course

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