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glutathione binding to iron Taming potentiates metallodrug action Glutathione dependent and independent ferroptosis

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In 1971, Judah Folkman, also referred to as the father of angiogenesis, hypothesized that angiogenesis was a factor that enables the growth of malignant tumors in cancer [98]

glutathione binding to iron Taming potentiates metallodrug action Glutathione dependent and independent ferroptosis

This was followed by dialysis using a dialysis bag with a molecular weight cutoff of 8000-14000 Da

glutathione binding to iron Taming potentiates metallodrug action Glutathione dependent and independent ferroptosis

60 GalluzziL.VitaleI.AaronsonS

glutathione binding to iron Taming potentiates metallodrug action Glutathione dependent and independent ferroptosis

In addition to MnO2, other transition metal oxides like Co3O4 and CeO2, which can react with GSH, can also be used to design GSH-responsive DDSs [69]

glutathione binding to iron Taming potentiates metallodrug action Glutathione dependent and independent ferroptosis

For patients experiencing injection site reactions, several practical strategies can minimize discomfort

glutathione binding to iron Taming potentiates metallodrug action Glutathione dependent and independent ferroptosis

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