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The two most important SH2 molecules at this point are the adaptor molecule Grb2 and the enzyme PI3K [251,252]

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The Systemic Immune Response to Trauma: An Overview of Pathophysiology and Treatment

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doi: 10.1021/cn300060v

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In fact, the involvement of theses neuropeptides in migraine disease is evident ( 11 C-PK11195 PET, indicating a neuroinflammatory process mediating one hallmark (CSD) of migraine disease

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