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[DOI] [PMC free article] [PubMed] [Google Scholar] 303.Barth, P

Lotz-Havla AS, Wei KJ, Schiergens KA, Brunet T, Kohlhase J, Regenauer-Vandewiele S, Maier EM

Simultaneously, AOD-9604 inhibits lipogenesis by downregulating enzymes involved in converting excess calories into stored fat

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When it comes to 1-MNAM, an often-overlooked product of vitamin B3 elimination, a newly published study found that 1-MNAM secreted by NNMT-expressing tumor cells was elevated in T cells and induced T cells to secrete the tumor-promoting cytokine tumor necrosis factor (TNF) in human ovarian cancer [52]