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Each of our men had a white paper in his hat, which in the darkness distinguished him from the enemy

In the central nervous system, chemotherapeutic agents also induce neuronal hyperexcitability in the spinal dorsal horn and anterior cingulate cortex leading to the development of central sensitization that causes CIPN

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They can for some people

Furthermore, the Common Terminology Criteria for Adverse Events 20 , which is used in most cancer clinical trials, is not a sensitive instrument for measuring neuropathy