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Kinase activity was assessed using the 2018 version of the UKA tool using basic parameters (Scan rank from 4 to 12, 500 permutations, 90% homology, equivalent weight for each database, minimal prediction score of 300)

These two residues are believed to influence the physicochemical properties and the redox potential of the active center and either enhance or impair the hydroxylation of monophenols by changing the ability of water molecules to deprotonate monophenolic substrates 21

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This process allows for tissue repair, restoration of cell homeostasis, and improvement of the bodys defense and adaptability