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10.1016/j.neuropharm.2008.07.024 22 BreslinF

Ann Med Surg

Additionally, prostaglandin E2 (PGE2) and leukotriene B4, produced by -6 polyunsaturated fatty acid, serve as pro-inflammatory lipid mediators that activate inflammatory vesicles and initiate the endoplasmic reticulum (ER) stress response (32)
Additional LPO products include F 2 -isoprostanes (F 2 -iPs), which are a group of prostaglandin F 2 -like compounds derived from the nonenzymatic oxidation of arachidonic acid

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