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Of interest, the down-expression of ACC2 results from an epigenetic process linked to histone deacetylation at the ACACB promoter by Sirtuin 1/6 that are activated by high cytosolic NAD + levels associated with enhanced FAO and reduced glucose metabolism

A 2016 meta-analysis showed that a low-calorie diet combined with carnitine supplementation promotes the oxidation of fat, spares muscle mass, and may also speed the rate of weight loss

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Lancet 12-13-1980;2(8207):1309-1310

X., Liu, C
