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scindens and other Clostridium enterica species were shown to utilize bile acid as a messenger to control the accumulation of chemokine-dependent hepatic NKT cells and antitumor immunity in the liver, thus protecting against both primary and metastatic liver cancer ( TCM and NPs have attracted increasing attention in the treatment of liver cancer, which is inseparable from their targeted modulation of gut microbiota ( Table 1 )

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