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Abnormal microglial activation, oxidative stress, and neuronal death are also associated with the progression of the disease

The capability of a system to withstand a manmade or natural hostile environment without suffering an abortive impairment of its ability to accomplish its dedicated mission

Simultaneously, autophagy plays a crucial role in antigen processing or presentation, which could reduce the expression of MHC class I molecules, which are abnormally downregulated in AA (50)

The impairment of the circadian rhythm during pregnancy compromises melatonin production, inhibiting the rhythm of melatonin release (74, 75)

doi:10.1021/cr300163e