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Clinical Chemistry 2011 57:2 (196-204) Pennell C., Westfall S

Vanyai et al, 2015)

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The resulting glutamate overstimulation of NMDA and metabotropic glutamate receptors (mGluRs) further complicates the situation, whereby mGluR activation via phospholipase C (PLC) and inositol trisphosphate (IP 3 ) signaling prompts Ca 2+ overload [138]

Based on the relationship between CVD and hydrostatic pressure and osmotic pressure, some researchers have speculated that the increase in TMAO in CVD is a compensatory response
