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Despite advances in understanding the cellular drivers of asthma, several fundamental features of the disease remain poorly explained

The tissue was then incubated in Hanks buffered salt solution (HBSS) containing 15 mM HEPES, 50 U/mL collagenase type II (Thermo Fisher 17101015), and 100 U/mL hyaluronidase (Sigma Aldrich H3506) at 37 C for 30 min

Results: The final review included six randomized controlled trials (Figure 1), summarized in Table 1