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Heme oxygenase-1 expression in endothelial cells leads to decreased expression of vascular cell adhesion molecule-1 (VCAM-1) as well as the expression and release of chemokines and proinflammatory cytokines such as CC-chemokine ligand (CCL)2, also known as MCP-1 (Sacerdoti et al., 2005)

They influence the initiation, progression, and resolution of neuroinflammation through multiple mechanisms, including the release of inflammatory mediators, regulation of immune cell infiltration, interactions with microglia and endothelial cells, inflammasome activation, extracellular matrix degradation, and phenotypic plasticity (Tastan and Heneka, 2024

Data Duplication: The extensive database can lead to duplicate entries for the same food item

In the models, the CO 2 concentration was fixed at 2.2 mM, considering CO 2 dissolved in plasma oscillated between 1.2 and 2.4 mM ( 2 concentration was incorporated into the Keq value of the equations of the enzymes that produce it (PDH, IDH, 2OGDH) as the ratio Keq / [CO 2 ] ( Supplementary Table S1 )

J Cell Physiol 233:6098