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Description
Sci Rep (2017) 7:46288
10.1074/jbc.M112.431973 J
Identification of a novel class of insect glutathione S-transferases involved in resistance to DDT in the malaria vector Anopheles gambiae
Target 300 to 400 mg elemental daily, working up gradually
The demonstration of an outward-open conformation in the crystal structure of the substrate-free form of dDAT is a corroboration of these biophysical and computational observations
