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doi: 10.1007/s00248-018-1232-y 63

Additionally, pioglitazone, another insulin-sensitizing drug that exerts its glucose-lowering effects through the activation of peroxisome proliferator-activated receptors, has also been reported to ameliorate cognitive decline

to improve the indices of cardiovascular, endocrine, immune and nervous systems, homeostasis and metabolism. The researchers observed a 1.6-1.8 fold decreased mortality rate in the epithalamin-treated group, as well as decreased rates of: Coronary artery disease Hypertension Osteoarthritis Osteoporosis The researchers concluded that epithalamin may be beneficial for health maintenance and age-related pathology prevention in elderly subjects

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(r,z)-3-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol 98
